Development and Formulation of Nanofiber-Based Ophthalmic Inserts for the Treatment of Fungal Keratitis
: These γ-CD and STC-enhanced AmphB-loaded PVA nanofiber-based ophthalmic inserts provide a non-invasive, rapidly dissolving ophthalmic dosage form that combines amorphous AmphB, immediate drug availability, and good ocular tolerance, supporting their further development as a patient-friendly treatment option for fungal keratitis.
Authors
- Balázs Pinke (ORCID: https://orcid.org/0000-0002-6683-6199)
- Romána Zelkó (ORCID: https://orcid.org/0000-0002-5419-9137)
- Safaa Omer
- Nándor Nagy (ORCID: https://orcid.org/0000-0002-6223-5214)
- László Mészáros (ORCID: https://orcid.org/0000-0001-5979-7403)
- Júlia Pongrácz (ORCID: https://orcid.org/0000-0003-4859-4656)
- Adrienn Kazsoki (ORCID: https://orcid.org/0009-0000-2648-3037)
- Katalin Kristóf
Institutions
- Semmelweis University (HU)
- Budapest University of Technology and Economics (HU)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2026-04-10
- DOI
- https://doi.org/10.3390/pharmaceutics18040464
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nemzeti Kutatási, Fejlesztési és Innovaciós Alap