Evidence Map of Pharmacologic and Non-Pharmacologic Perioperative Strategies for Managing Acute Postoperative Pain After Laparoscopic Surgery, 2012–2025: The M-PALS Collaborative
Interventions for M-PALS appear safe, with no RCT indicating worse efficacy of intervention than usual care; but evidence regarding superiority is conflicting. Future research should establish standardized and longer-term core outcome sets and make head-to-head comparisons between optimal strategies.
Authors
- Miranda Considine
- Shahnaz Sultan (ORCID: https://orcid.org/0000-0002-5867-8741)
- Sallee Brandt
- Timothy J Wilt (ORCID: https://orcid.org/0000-0002-6019-7779)
- Amy M. Claussen (ORCID: https://orcid.org/0000-0003-3996-1055)
- Bronwyn Southwell
- Romil R Parikh (ORCID: https://orcid.org/0000-0001-6087-0583)
- Christopher J. Tignanelli
- Drew J. Persson
- Christie L. Martin (ORCID: https://orcid.org/0000-0003-1685-0205)
- Elizabeth Wick (ORCID: https://orcid.org/0000-0002-0928-5407)
- Luz Angela Choconta-Piraquive
- Swathi Pagadala
- Gabriella L. Lott
- Peter Sawtell
- Aaron A Berg
- Adalyn J. Scherer
- Mary E. Butler
- Genevieve B. Melton
Institutions
- University of Minnesota (US)
- University of California, San Francisco (US)
- University of Minnesota System (US)
- Twin Cities Orthopedics (US)
- Minneapolis VA Health Care System (US)
- University of Minnesota Medical Center (US)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2026-04-10
- DOI
- https://doi.org/10.3390/jcm15082872
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Minnesota
- U.S. Food and Drug Administration