Rapid Response, Unexpected Risk: A ROS1-Positive Non-Small Cell Lung Cancer (NSCLC) Case with Lazarus Syndrome and Fatal Thrombosis
A 57-year-old woman with a ROS1-rearranged NSCLC patient demonstrated a Lazarus response to crizotinib but later developed recurrent pulmonary embolism (PE) with right ventricular (RV) failure. This incident highlights the potential crizotinib-related thrombotic risk and the need for appropriate monitoring of vascular complications, particularly in limited-option settings such as Thailand.
Authors
- P. Eiamprapaporn
- Piraya Patrathiranond
- Sasipim Thitvirachawat
Institutions
- Thammasat University Hospital (TH)
Publication Details
- Journal
- Asian Medical Journal and Alternative Medicine
- Published
- 2026-04-10
- DOI
- https://doi.org/10.70933/2773-9465.1331
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00