Metastatic Cholangiocarcinoma Presenting With Chronic Hip Pain

CASE: A 59-year-old woman presented with chronic right hip pain. Initial radiographs and CT scans were negative, but magnetic resonance imaging revealed extensive bone marrow oedema. Elevated serum CA 19-9 (3,581 kU/L) initiated further investigation, which identified an iCCA with acetabular metastasis. This case reports a rare instance of acetabular metastases from a cholangiocarcinoma. CONCLUSION: Since medullary bone lesions may remain occult on plain radiographs and CT, physicians must look beyond negative imaging to avoid diagnostic delays. Persistent bone pain unresponsive to conservative treatment warrants advanced imaging and systemic staging, regardless of initial findings or absence of systemic symptoms.

Authors

Institutions

Publication Details

Journal
JBJS Case Connector
Published
2026-04-01
DOI
https://doi.org/10.2106/jbjs.cc.25.00632
Primary Topic
Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Metastatic Cholangiocarcinoma Presenting With Chronic Hip Pain

John Van Overschelde, Dries Verbeke, Ine Goethals
JBJS Case Connector
Cancer Diagnosis and Treatment
article

Metastatic Cholangiocarcinoma Presenting With Chronic Hip Pain

John Van Overschelde, Dries Verbeke, Ine Goethals
article en

Abstract

CASE: A 59-year-old woman presented with chronic right hip pain. Initial radiographs and CT scans were negative, but magnetic resonance imaging revealed extensive bone marrow oedema. Elevated serum CA 19-9 (3,581 kU/L) initiated further investigation, which identified an iCCA with acetabular metastasis. This case reports a rare instance of acetabular metastases from a cholangiocarcinoma. CONCLUSION: Since medullary bone lesions may remain occult on plain radiographs and CT, physicians must look beyond negative imaging to avoid diagnostic delays. Persistent bone pain unresponsive to conservative treatment warrants advanced imaging and systemic staging, regardless of initial findings or absence of systemic symptoms.

JBJS Case ConnectorVol. 16(2)
Ghent University (BE), Onze Lieve Vrouwziekenhuis Hospital (BE)
Good health and well-being, Gender equality
Openalex Percentile: Top 19%
Cancer Diagnosis and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.