New insights into the chemical composition and biological activities of Lawsonia inermis seeds and leaves: a comparative study

of 80.1 µg/mL being obtained in the case of DPPH and ABTS respectively although the seeds registered a little lower value, indicating the abundance of phenolic compounds. In addition, seed and leaf extracts had good antimicrobial activities with minimum inhibitory concentrations (MIC) that fell below 10 mg/mL against bacterial strains including Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae. Correlation analysis suggested a strong relationship between phenolic content and antioxidant activity, although this analysis was conducted on a limited dataset. These results indicate that Moroccan L. inermis seeds and leaves have high concentrations of bioactive compounds. They also highlight the potential of henna seeds as a novel source of bioactive ingredients for cosmetics or pharmacy products and have a good potential of natural therapeutic and cosmetic use.

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Publication Details

Journal
Scientific Reports
Published
2026-04-11
DOI
https://doi.org/10.1038/s41598-026-47202-5
Primary Topic
Bioactive Compounds and Antitumor Agents
Type
article
Field-Weighted Citation Impact
0.00

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article

New insights into the chemical composition and biological activities of Lawsonia inermis seeds and leaves: a comparative study

Saïd Gharby, Asmaa Oubihi, Chaimae El Kourchı, Hicham Harhar et al.
Scientific Reports
Bioactive Compounds and Antitumor Agents
article

New insights into the chemical composition and biological activities of Lawsonia inermis seeds and leaves: a comparative study

Saïd Gharby, Asmaa Oubihi, Chaimae El Kourchı, Hicham Harhar, Zoubida Charrouf, Waleed Al Abdulmonem, Abdelhakim Bouyahya, Ahmed Hajib, Issmail Nounah, Otmane Aissaoui
article en

Abstract

of 80.1 µg/mL being obtained in the case of DPPH and ABTS respectively although the seeds registered a little lower value, indicating the abundance of phenolic compounds. In addition, seed and leaf extracts had good antimicrobial activities with minimum inhibitory concentrations (MIC) that fell below 10 mg/mL against bacterial strains including Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae. Correlation analysis suggested a strong relationship between phenolic content and antioxidant activity, although this analysis was conducted on a limited dataset. These results indicate that Moroccan L. inermis seeds and leaves have high concentrations of bioactive compounds. They also highlight the potential of henna seeds as a novel source of bioactive ingredients for cosmetics or pharmacy products and have a good potential of natural therapeutic and cosmetic use.

Scientific Reports
Mohammed V University (MA), Qassim University (SA), Université Ibn-Tofail (MA), Université Ibn Zohr (MA), Buraydah Colleges (SA)
Qassim University
Zero hunger
Openalex Percentile: Top 23%
Bioactive Compounds and Antitumor Agents
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