Endothelial progenitor cell numbers vary in newborns and adults; anti-gm-CSFα (CD116) antibody as a novel marker for EPC enumeration
< 0.001).ConclusionEPC numbers are significantly higher in newborns than in adults, suggesting an important developmental role for these cells. The GM-CSFα-specific antibody (CD116) may serve as a novel auxiliary marker for the identification and quantification of circulating EPCsubpopulations. Furthermore, EPC numbers appear to vary across different life stages, with higher numbers in newborns potentially reflecting the presence of a highly regenerative microenvironment.
Authors
- Çağatay Karaca (ORCID: https://orcid.org/0000-0002-7839-9694)
- Nezihe Köker (ORCID: https://orcid.org/0000-0002-3962-9397)
- Mustafa Yavuz Köker (ORCID: https://orcid.org/0000-0001-7061-8525)
- Sevil Şimşek
- Adnan Öztürk
Institutions
- Inonu University (TR)
- Kayseri Eğitim ve Araştırma Hastanesi (TR)
- Erciyes University (TR)
Publication Details
- Journal
- Innate Immunity
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1177/17534259261438615
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Erciyes Üniversitesi
- Bilimsel Araştırma Projeleri, Erciyes Üniversitesi