Safety and efficacy of a feed additive consisting of l‐histidine monohydrochloride monohydrate produced with Escherichia coli CCTCC M 20241089 for all animal species (Anhui Huaheng Biotechnology Co., Ltd)

CCTCC M 20241089 in animal nutrition was considered safe for the consumers of products from animals receiving the additive, and for the environment. The FEEDAP Panel could not conclude on the potential of the additive to be an irritant to skin and/or eyes and to be a potential skin sensitiser. The additive was regarded as an effective source of the amino acid L-histidine for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.

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Publication Details

Journal
EFSA Journal
Published
2026-04-01
DOI
https://doi.org/10.2903/j.efsa.2026.10032
Primary Topic
Agricultural safety and regulations
Type
article
Field-Weighted Citation Impact
0.00

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article

Safety and efficacy of a feed additive consisting of l‐histidine monohydrochloride monohydrate produced with Escherichia coli CCTCC M 20241089 for all animal species (Anhui Huaheng Biotechnology Co., Ltd)

E. Bonos, Matteo Lorenzo Innocenti, Boet Glandorf, Maryline Kouba et al.
EFSA Journal
Agricultural safety and regulations
article

Safety and efficacy of a feed additive consisting of l‐histidine monohydrochloride monohydrate produced with Escherichia coli CCTCC M 20241089 for all animal species (Anhui Huaheng Biotechnology Co., Ltd)

E. Bonos, Matteo Lorenzo Innocenti, Boet Glandorf, Maryline Kouba, Ronette Gehring, Carlo Nebbia, Marta López‐Alonso, Birgit Dusemund, Jordi Tarrés‐Call, Montserrat Anguita, EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Mojca Durjava, Alena Pechová, Henrik Christensen, Roberto Edoardo Villa, Giovanna Azimonti, Elisa Pettenati, Miguel Prieto‐Maradona, Katerina Theodoridou, Francesca Marcon
article en

Abstract

CCTCC M 20241089 in animal nutrition was considered safe for the consumers of products from animals receiving the additive, and for the environment. The FEEDAP Panel could not conclude on the potential of the additive to be an irritant to skin and/or eyes and to be a potential skin sensitiser. The additive was regarded as an effective source of the amino acid L-histidine for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.

EFSA JournalVol. 24(4)
European Food Safety Authority
Openalex Percentile: Top 27%
Agricultural safety and regulations
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