Half-duration tourniquet plus intra-articular tranexamic acid injection reduces blood loss and improves early recovery after total knee arthroplasty

= 0.734).ConclusionIn total knee arthroplasty patients, the combination of a half-duration tourniquet with intra-articular tranexamic acid may provide superior perioperative blood management compared with a full-duration tourniquet or half-duration tourniquet alone. This strategy may reduce total and hidden postoperative blood loss, reduce hemoglobin loss, and lower transfusion rates. Additionally, it may reduce postoperative pain and promote earlier recovery of knee function. In addition, this treatment combination did not cause a significant increase in complications, including thrombosis or infection.

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Publication Details

Journal
Journal of International Medical Research
Published
2026-04-01
DOI
https://doi.org/10.1177/03000605261436578
Primary Topic
Blood transfusion and management
Type
article
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article

Half-duration tourniquet plus intra-articular tranexamic acid injection reduces blood loss and improves early recovery after total knee arthroplasty

F. Liu, Xingyu Wang, Ning Wang, Bingchi He et al.
Journal of International Medical Research
Blood transfusion and management
article

Half-duration tourniquet plus intra-articular tranexamic acid injection reduces blood loss and improves early recovery after total knee arthroplasty

F. Liu, Xingyu Wang, Ning Wang, Bingchi He, Futeng Wang, Shuhan Jia
article en

Abstract

= 0.734).ConclusionIn total knee arthroplasty patients, the combination of a half-duration tourniquet with intra-articular tranexamic acid may provide superior perioperative blood management compared with a full-duration tourniquet or half-duration tourniquet alone. This strategy may reduce total and hidden postoperative blood loss, reduce hemoglobin loss, and lower transfusion rates. Additionally, it may reduce postoperative pain and promote earlier recovery of knee function. In addition, this treatment combination did not cause a significant increase in complications, including thrombosis or infection.

Journal of International Medical ResearchVol. 54(4)
Central Hospital Affiliated to Shenyang Medical College (CN)
Good health and well-being
Openalex Percentile: Top 27%
Blood transfusion and management
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