Clinical approaches to hypersomnolence complaints in psychiatry: A narrative review

BACKGROUND: Hypersomnolence complaints are common in psychiatric disorders and carry substantial functional burden, yet they remain under-recognized and frequently under-investigated. Clinically, hypersomnolence spans three partially overlapping dimensions: excessive daytime sleepiness, excessive total sleep time/need for sleep, and sleep (wake) inertia. OBJECTIVE: To provide a pragmatic, clinician-oriented framework for evaluating and managing hypersomnolence complaints in psychiatry, integrating sleep medicine concepts with psychiatric comorbidity and real-world care pathways. METHODS: Narrative synthesis of epidemiological, clinical, and translational evidence with emphasis on: (i) precise phenotypic clarification of the complaint; (ii) systematic etiological work-up (sleep debt and circadian misalignment, depressive episodes, ADHD, anxiety/trauma-related disorders, iatrogenic factors, OSA, RLS, parasomnias, narcolepsy/idiopathic hypersomnia); and (iii) stepwise management strategies. RESULTS: Hypersomnolence affects 40-50% of patients in major depressive episodes and is frequently linked to circadian factors, insomnia comorbidity, obstructive sleep apnea, and medication effects. Objective long sleep time is common among depressed patients with hypersomnolence. Similar observations are made for ADHD, anxiety and trauma-related disorders and psychotics disorders. A three-step care algorithm is proposed: (1) universal behavioral/circadian measures; (2) targeted treatment of the underlying cause (e.g., antidepressant optimization, chronotherapeutics, CBT-I, CPAP/MAD for OSA, specific management for RLS/parasomnias, and specialist evaluation for narcolepsy/idiopathic hypersomnia); (3) management of residual symptoms (e.g., light therapy; carefully selected wake-promoting agents when indicated). CONCLUSIONS: A fine-grained clinical characterization coupled with systematic etiological screening improves diagnosis and treatment of hypersomnolence in psychiatry. Integrating sleep-specific tools (actigraphy, sleep diaries, MSLT/PSG when appropriate) with psychiatric assessment supports personalized, mechanism-informed care and may reduce morbidity, accident risk, and healthcare utilization.

Authors

Institutions

Publication Details

Journal
L Encéphale
Published
2026-04-01
DOI
https://doi.org/10.1016/j.encep.2026.03.002
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Clinical approaches to hypersomnolence complaints in psychiatry: A narrative review

Nausicaa Christodoulou, Pierre A. Geoffroy, Jean‐Arthur Micoulaud Franchi, Julia Maruani
L Encéphale
Sleep and Wakefulness Research
article

Clinical approaches to hypersomnolence complaints in psychiatry: A narrative review

Nausicaa Christodoulou, Pierre A. Geoffroy, Jean‐Arthur Micoulaud Franchi, Julia Maruani
article en

Abstract

BACKGROUND: Hypersomnolence complaints are common in psychiatric disorders and carry substantial functional burden, yet they remain under-recognized and frequently under-investigated. Clinically, hypersomnolence spans three partially overlapping dimensions: excessive daytime sleepiness, excessive total sleep time/need for sleep, and sleep (wake) inertia. OBJECTIVE: To provide a pragmatic, clinician-oriented framework for evaluating and managing hypersomnolence complaints in psychiatry, integrating sleep medicine concepts with psychiatric comorbidity and real-world care pathways. METHODS: Narrative synthesis of epidemiological, clinical, and translational evidence with emphasis on: (i) precise phenotypic clarification of the complaint; (ii) systematic etiological work-up (sleep debt and circadian misalignment, depressive episodes, ADHD, anxiety/trauma-related disorders, iatrogenic factors, OSA, RLS, parasomnias, narcolepsy/idiopathic hypersomnia); and (iii) stepwise management strategies. RESULTS: Hypersomnolence affects 40-50% of patients in major depressive episodes and is frequently linked to circadian factors, insomnia comorbidity, obstructive sleep apnea, and medication effects. Objective long sleep time is common among depressed patients with hypersomnolence. Similar observations are made for ADHD, anxiety and trauma-related disorders and psychotics disorders. A three-step care algorithm is proposed: (1) universal behavioral/circadian measures; (2) targeted treatment of the underlying cause (e.g., antidepressant optimization, chronotherapeutics, CBT-I, CPAP/MAD for OSA, specific management for RLS/parasomnias, and specialist evaluation for narcolepsy/idiopathic hypersomnia); (3) management of residual symptoms (e.g., light therapy; carefully selected wake-promoting agents when indicated). CONCLUSIONS: A fine-grained clinical characterization coupled with systematic etiological screening improves diagnosis and treatment of hypersomnolence in psychiatry. Integrating sleep-specific tools (actigraphy, sleep diaries, MSLT/PSG when appropriate) with psychiatric assessment supports personalized, mechanism-informed care and may reduce morbidity, accident risk, and healthcare utilization.

L Encéphale
Centre National de la Recherche Scientifique (FR), Université de Bordeaux (FR), Inserm (FR), Assistance Publique – Hôpitaux de Paris (FR), Bordeaux Population Health (FR), Institut de Psychiatrie et Neurosciences de Paris (FR), FHU Neurovasc (FR), Hôpital Bichat-Claude-Bernard (FR), NeuroDiderot (FR)
Openalex Percentile: Top 25%
Sleep and Wakefulness Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.