Deep eutectic solvent and improved needle filter-based liquid-membrane microextraction combined with high performance liquid chromatography for the determination of sulfonamide and fluoroquinolone residues in milk

=6）. This method has been successfully applied to the determination of four antibiotics in commercially available milk products. The spiked recoveries for the four antibiotics at high， medium and low levels ranged from 88.9% to 113.4%. The proposed method is accurate， simple， sensitive and eco-friendly， and could be a good reference to the development of new analytical method for antibiotic residues in dairy products.