Antioxidant Effect of Methylene chloride Fraction of the Guzeunggupo-processed Curcuma longa L. in Caenorhabditis elegans

In the process of searching for antioxidants in plants, the methylene chloride fraction of guzeungupo-processed Curcuma longa L. was observed to have a strong scavenging effect on DPPH radicals. In the study using Caenorhabditis elegans, the methylene chloride fraction reduced the level of reactive oxygen species (ROS), while the oxidative stress resistances of superoxide dismutase (SOD) and catalase were improved. The methylene chloride fraction was also found to cause the transgenic strain CF1553 to produce resistant proteins that resist oxidative stress.

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Publication Details

Journal
Korean Journal of Pharmacognosy
Published
2026-03-31
DOI
https://doi.org/10.22889/kjp.2026.57.1.54
Primary Topic
Curcumin's Biomedical Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Antioxidant Effect of Methylene chloride Fraction of the Guzeunggupo-processed Curcuma longa L. in Caenorhabditis elegans

Nam-Jin Ju, Hyo-Jung Kim, Jun-Hyeong Kim, Dae-Keun Kim et al.
Korean Journal of Pharmacognosy
Curcumin's Biomedical Applications
article

Antioxidant Effect of Methylene chloride Fraction of the Guzeunggupo-processed Curcuma longa L. in Caenorhabditis elegans

Nam-Jin Ju, Hyo-Jung Kim, Jun-Hyeong Kim, Dae-Keun Kim, Ji-Woo Choi
article en

Abstract

In the process of searching for antioxidants in plants, the methylene chloride fraction of guzeungupo-processed Curcuma longa L. was observed to have a strong scavenging effect on DPPH radicals. In the study using Caenorhabditis elegans, the methylene chloride fraction reduced the level of reactive oxygen species (ROS), while the oxidative stress resistances of superoxide dismutase (SOD) and catalase were improved. The methylene chloride fraction was also found to cause the transgenic strain CF1553 to produce resistant proteins that resist oxidative stress.

Korean Journal of PharmacognosyVol. 57(1)
Ministry of Education
Openalex Percentile: Top 22%
Curcumin's Biomedical Applications
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