Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties (Adv. Funct. Mater. 28/2026)
Long-Lasting Dual-Functional Antiviral Oligomers In their Research Article (10.1002/adfm.202506704), Shady Farah and co-authors successfully develop a library of dual-functional antiviral oligomers incorporating N-halamine and quaternary ammonium functionalities for long-lasting antiviral activity. The leading materials exhibit rapid and durable antiviral activity against SARS-CoV-2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 concentration, surpassing household bleach, while remaining non-toxic to human cells.
Authors
- Nofar Atari (ORCID: https://orcid.org/0000-0002-5819-0033)
- Merna Shaheen‐Mualim
- Shady Farah (ORCID: https://orcid.org/0000-0002-9801-5301)
- Simran Jindal (ORCID: https://orcid.org/0000-0002-5602-8518)
- Bassma Khamaisi (ORCID: https://orcid.org/0000-0002-5129-8551)
- Ranabir Majumder (ORCID: https://orcid.org/0000-0003-3585-3276)
- Konda Reddy Kunduru (ORCID: https://orcid.org/0000-0001-6422-647X)
- Eid Nassar‐Marjiya (ORCID: https://orcid.org/0009-0003-1085-6267)
- Luna Rizik (ORCID: https://orcid.org/0000-0002-8733-3646)
- Mahitosh Mandal
- Neta Kutner
- Mahran Daifa
- Krishanu Ghosal (ORCID: https://orcid.org/0000-0003-3399-1413)
- Michal Mandelboim (ORCID: https://orcid.org/0000-0002-5997-7241)
- Qi Wu
Institutions
- Indian Institute of Technology Kharagpur (IN)
- Tel Aviv University (IL)
- Technion – Israel Institute of Technology (IL)
- Sheba Medical Center (IL)
- Israel Ministry of Health (IL)
Publication Details
- Journal
- Advanced Functional Materials
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1002/adfm.74838
- Primary Topic
- Antimicrobial agents and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00