Association of <i>PTPN22</i> and <i>NLRP3</i> Gene Polymorphisms with Psoriasis Susceptibility in a Han Chinese Population
OBJECTIVE: ) and genetic susceptibility to psoriasis in the Jiujiang population. METHODS: rs10754558 genotypes. Logistic regression analysis was conducted to evaluate the associations between the genotypes, alleles, and genetic models of these three loci and psoriasis susceptibility. The associations between these polymorphisms and disease subtypes or severity were also explored. RESULTS: > 0.05). CONCLUSIONS: rs2488457 locus may be key factors influencing psoriasis susceptibility.
Authors
- Xia Wei (ORCID: https://orcid.org/0000-0001-7198-0825)
- Liangliang Ouyang
- Yafeng Tan
- Fusheng Xie
- Tao Jiang
Institutions
- Jiujiang University (CN)
- Yangtze University (CN)
Publication Details
- Journal
- Genetic Testing and Molecular Biomarkers
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1177/19450265261440160
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00