Risk factors for adjacent vertebral fracture after PVP in patients with OVCF

Objective: To identify the risk factors and evaluate the predictive performance for adjacent vertebral fracture (AVF) after Percutaneous vertebroplasty (PVP). Methods: < 0.05), which were subsequently entered into a binary logistic regression model to determine independent risk factors. Predictive performance was assessed using receiver operating characteristic (ROC) curve analysis. Results: < 0.001) were independent risk factors. predictive performance analysis showed that age had an AUC of 0.623 (sensitivity 56.6%, specificity 62.6%), and BMD had an AUC of 0.629 (sensitivity 86.0%, specificity 39.9%). A combined prediction model achieved an AUC of 0.706 (95% CI: 0.565-0.976). Conclusion: Advanced age and low bone mineral density are independent risk factors for AVF after PVP, with OR = 1.045 per year of age and OR = 2.85 per SD decrease in BMD T-score. Although the predictive value of individual indicators is limited (AUC < 0.7), a comprehensive model (AUC = 0.706) achieves moderate accuracy suitable for preliminary risk stratification, supporting the prioritization of systemic osteoporosis management over surgical technical details in prevention strategies.