Case Report: Neurologic signs following rattlesnake envenomation

), a subspecies of the Western Rattlesnake, is the most widespread rattlesnake in California (1). A 5-year-old miniature horse mare presented for a presumed Western Rattlesnake bite. The owners found the horse the morning of presentation with severe facial swelling and the horse was housed in an area where rattlesnakes are commonly observed. The horse was reported to be normal the day prior to presentation. On blood examination, severe thrombocytopenia, elevated AST, and elevated creatine kinase (CK) were identified. On physical examination the horse was noted to have severe facial swelling, to be dribbling urine, and to have a hypermetric gate in the hind limbs. Treatment was initiated with antivenom, bethanechol, and supportive care. After 6 days of hospitalization, the horse regained urinary function, the facial swelling significantly improved, the neurologic gait resolved, and the horse was discharged. This is the first case report describing neurologic manifestations from a presumed Western Rattlesnake bite.

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Publication Details

Journal
Frontiers in Veterinary Science
Published
2026-04-07
DOI
https://doi.org/10.3389/fvets.2026.1756610
Primary Topic
Venomous Animal Envenomation and Studies
Type
article
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article

Case Report: Neurologic signs following rattlesnake envenomation

Jessica Bouton, C. Langdon Fielding, Diane Rhodes, Laura Weintraub
Frontiers in Veterinary Science
Venomous Animal Envenomation and Studies
article

Case Report: Neurologic signs following rattlesnake envenomation

Jessica Bouton, C. Langdon Fielding, Diane Rhodes, Laura Weintraub
article en

Abstract

), a subspecies of the Western Rattlesnake, is the most widespread rattlesnake in California (1). A 5-year-old miniature horse mare presented for a presumed Western Rattlesnake bite. The owners found the horse the morning of presentation with severe facial swelling and the horse was housed in an area where rattlesnakes are commonly observed. The horse was reported to be normal the day prior to presentation. On blood examination, severe thrombocytopenia, elevated AST, and elevated creatine kinase (CK) were identified. On physical examination the horse was noted to have severe facial swelling, to be dribbling urine, and to have a hypermetric gate in the hind limbs. Treatment was initiated with antivenom, bethanechol, and supportive care. After 6 days of hospitalization, the horse regained urinary function, the facial swelling significantly improved, the neurologic gait resolved, and the horse was discharged. This is the first case report describing neurologic manifestations from a presumed Western Rattlesnake bite.

Frontiers in Veterinary ScienceVol. 13
Life below water
Openalex Percentile: Top 28%
Venomous Animal Envenomation and Studies
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