Compatible Fluorescent-Afterglow Luminescent Probe Enables Quantification of Photochemical Reaction-Driven Tumor Theranostics

can be consecutively visualized through fluorescence and afterglow imaging, respectively, so that the initial time, light intensity, and duration in PDT treatment can be accurately quantified in real-time. Besides, the established correlation between FL/AF intensity and photodynamic therapeutic efficacy will provide an opportunity to noninvasively guide precise treatment plans and achieve more effective treatment outcomes. Thus, this study not only presents strategies for quantitatively controlling of tumor PDT, but also provides a promising FL/AF scaffold for imaging of other disease evaluation.