Cocaine-Induced Cardiomyopathy as a Rare Etiology of Severe Heart Failure in Young Adults: A Case Report

Cocaine use is well known to cause acute cardiovascular events, but chronic cardiomyopathy is a less common consequence. We present a 27-year-old male with five years of cocaine use who developed acute decompensated heart failure, marked by severe biventricular dilation, an ejection fraction of 19%, pulmonary hypertension, and multiorgan congestion. After inpatient stabilization, he was started on guideline-directed medical therapy and abstained from cocaine. This case underscores that even profound cardiac dysfunction from cocaine can be substantially reversible with early recognition, aggressive therapy, and substance cessation.

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Publication Details

Journal
Cureus
Published
2026-04-07
DOI
https://doi.org/10.7759/cureus.106598
Primary Topic
Forensic Toxicology and Drug Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Cocaine-Induced Cardiomyopathy as a Rare Etiology of Severe Heart Failure in Young Adults: A Case Report

Melkon Hacobian, Pranali R Dave
Cureus
Forensic Toxicology and Drug Analysis
article

Cocaine-Induced Cardiomyopathy as a Rare Etiology of Severe Heart Failure in Young Adults: A Case Report

Melkon Hacobian, Pranali R Dave
article en

Abstract

Cocaine use is well known to cause acute cardiovascular events, but chronic cardiomyopathy is a less common consequence. We present a 27-year-old male with five years of cocaine use who developed acute decompensated heart failure, marked by severe biventricular dilation, an ejection fraction of 19%, pulmonary hypertension, and multiorgan congestion. After inpatient stabilization, he was started on guideline-directed medical therapy and abstained from cocaine. This case underscores that even profound cardiac dysfunction from cocaine can be substantially reversible with early recognition, aggressive therapy, and substance cessation.

CureusVol. 18(4)
University of California, Los Angeles (US), Arrowhead Regional Medical Center (US)
Good health and well-being
Openalex Percentile: Top 33%
Forensic Toxicology and Drug Analysis
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