First description of an orthotopically located spontaneously ruptured non-seminomatous, metastatic germ cell tumor and review of literature

Spontaneous rupture of a testicular tumour is extremely rare. We report a 51-year-old man presenting with rapid, painless scrotal swelling without trauma. Imaging showed a ruptured left testicular mass with extensive hematoma, emergency exploration confirmed tumour perforation. Histology revealed a yolk sac-predominant non-seminomatous germ cell tumour. While initial staging was negative, early restaging before adjuvant therapy identified a new pulmonary metastasis. The patient received three cycles of BEP chemotherapy and achieved complete remission. He remains disease-free at two-year follow-up. This case emphasises prompt evaluation and early restaging in atypical acute scrotal presentations.

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Publication Details

Journal
Urology Case Reports
Published
2026-04-07
DOI
https://doi.org/10.1016/j.eucr.2026.103437
Primary Topic
Testicular diseases and treatments
Type
article
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article

First description of an orthotopically located spontaneously ruptured non-seminomatous, metastatic germ cell tumor and review of literature

Jonas Jarczyk, Philipp Nuhn, Pernilla Virginia Conrad, Katharina Vogt et al.
Urology Case Reports
Testicular diseases and treatments
article

First description of an orthotopically located spontaneously ruptured non-seminomatous, metastatic germ cell tumor and review of literature

Jonas Jarczyk, Philipp Nuhn, Pernilla Virginia Conrad, Katharina Vogt, Jakob Kohler, Leonhard Buck, Dithild-Angelika Melchior, Konrad Hügelmann, Severin Rodler, Julian Risch
article en

Abstract

Spontaneous rupture of a testicular tumour is extremely rare. We report a 51-year-old man presenting with rapid, painless scrotal swelling without trauma. Imaging showed a ruptured left testicular mass with extensive hematoma, emergency exploration confirmed tumour perforation. Histology revealed a yolk sac-predominant non-seminomatous germ cell tumour. While initial staging was negative, early restaging before adjuvant therapy identified a new pulmonary metastasis. The patient received three cycles of BEP chemotherapy and achieved complete remission. He remains disease-free at two-year follow-up. This case emphasises prompt evaluation and early restaging in atypical acute scrotal presentations.

Urology Case ReportsVol. 66
University Hospital Schleswig-Holstein (DE), University of Lübeck (DE)
Good health and well-being
Openalex Percentile: Top 26%
Testicular diseases and treatments
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