Surgical Release of the Carpal Tunnel in a Patient with Compressive Median Neuropathy: A Case Report

Carpal tunnel syndrome (CTS) is the most common compressive neuropathy of the upper extremity and frequently coexists with other fibroproliferative disorders of the hand, particularly in patients with metabolic conditions such as diabetes mellitus. Trigger finger, a stenosing tenosynovitis caused by thickening of the A1 pulley, shares pathophysiological mechanisms with CTS, including collagen glycosylation and connective tissue alterations. We report the case of a 52-year-old right-handed woman with poorly controlled type 2 diabetes mellitus who presented with an 18-month history of progressive paresthesias in the median nerve distribution of the right hand, nocturnal pain, and decreased grip strength, associated with symptomatic triggering of the fifth digit. Physical examination and nerve conduction studies confirmed moderate to severe median nerve compression at the carpal tunnel. The patient underwent open carpal tunnel release combined with A1 pulley release of the fifth digit in a single operative session under regional anesthesia. Intraoperative findings included a thickened transverse carpal ligament and a flattened median nerve without structural disruption, as well as a fibrotic A1 pulley. Postoperatively, the patient experienced complete resolution of nocturnal pain and triggering, with progressive sensory recovery and restoration of thumb opposition strength at six-week follow-up. No complications were observed. This case highlights the frequent coexistence of CTS and trigger finger in diabetic patients and supports the safety and effectiveness of combined surgical management in a single procedure. Early recognition and comprehensive treatment of associated hand pathologies may improve functional outcomes and patient satisfaction.

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Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-04-06
DOI
https://doi.org/10.5281/zenodo.19449647
Primary Topic
Peripheral Nerve Disorders
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article
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article

Surgical Release of the Carpal Tunnel in a Patient with Compressive Median Neuropathy: A Case Report

Sergio Morales Acosta, Diego Armando Fabela Martínez, Damián Hernández Bonilla, Joksan Vargas López et al.
Zenodo (CERN European Organization for Nuclear Research)
Peripheral Nerve Disorders
article

Surgical Release of the Carpal Tunnel in a Patient with Compressive Median Neuropathy: A Case Report

Sergio Morales Acosta, Diego Armando Fabela Martínez, Damián Hernández Bonilla, Joksan Vargas López, Luz Maria Ortega Sandoval, Alejandra Trujillo Astudillo, Ximena Alejandra Flores Salinas, Ángel de Jesús Ramos Fuentes, Angel Mijátovic García Ramírez
article en

Abstract

Carpal tunnel syndrome (CTS) is the most common compressive neuropathy of the upper extremity and frequently coexists with other fibroproliferative disorders of the hand, particularly in patients with metabolic conditions such as diabetes mellitus. Trigger finger, a stenosing tenosynovitis caused by thickening of the A1 pulley, shares pathophysiological mechanisms with CTS, including collagen glycosylation and connective tissue alterations. We report the case of a 52-year-old right-handed woman with poorly controlled type 2 diabetes mellitus who presented with an 18-month history of progressive paresthesias in the median nerve distribution of the right hand, nocturnal pain, and decreased grip strength, associated with symptomatic triggering of the fifth digit. Physical examination and nerve conduction studies confirmed moderate to severe median nerve compression at the carpal tunnel. The patient underwent open carpal tunnel release combined with A1 pulley release of the fifth digit in a single operative session under regional anesthesia. Intraoperative findings included a thickened transverse carpal ligament and a flattened median nerve without structural disruption, as well as a fibrotic A1 pulley. Postoperatively, the patient experienced complete resolution of nocturnal pain and triggering, with progressive sensory recovery and restoration of thumb opposition strength at six-week follow-up. No complications were observed. This case highlights the frequent coexistence of CTS and trigger finger in diabetic patients and supports the safety and effectiveness of combined surgical management in a single procedure. Early recognition and comprehensive treatment of associated hand pathologies may improve functional outcomes and patient satisfaction.

Zenodo (CERN European Organization for Nuclear Research)
Universidad Veracruzana (MX), Universidad de San Carlos de Guatemala (GT), Universidad Autónoma de Nuevo León (MX), Universidad de Guadalajara (MX), Herzgefäss Medizin Klinik Im Park (CH), St Bernard's Hospital (GI), Universidad Anáhuac (MX), Instituto Politécnico Nacional (MX)
Good health and well-being
Openalex Percentile: Top 5%
Peripheral Nerve Disorders
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