Increased Risk of Central Mesocolic Lymph Node Metastases in BRAF-Mutated Stage I-III Colon Cancer
: BRAF mutations in primary CC are linked to higher rates of intermediate and central LNMs. Patients with BRAF-mutated tumors may benefit from extended lymphadenectomy. Future randomized trials should evaluate biomarker-driven surgical strategies in CC.
Authors
- Rasa Sabaliauskaitė (ORCID: https://orcid.org/0000-0002-3465-3558)
- Kristina Marcinkevičiūtė
- Ugnius Mickys (ORCID: https://orcid.org/0000-0001-7805-0727)
- Rokas Stulpinas (ORCID: https://orcid.org/0000-0002-9361-6562)
- Justas Kuliavas (ORCID: https://orcid.org/0000-0001-8503-1495)
- Augustinas Baušys (ORCID: https://orcid.org/0000-0003-1848-2960)
- Ieva Vaicekauskaitė (ORCID: https://orcid.org/0000-0003-3536-4384)
- Kestutis Strupas
- Audrius Dulskas
Institutions
- Vilnius University (LT)
- National Cancer Institute (LT)
- Vilnius University Hospital Santariskiu Klinikos (LT)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2026-04-06
- DOI
- https://doi.org/10.3390/jcm15072766
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00