Inorganic Antimicrobial Materials

Infectious diseases caused by various pathogens pose a major threat throughout human history. While antibiotics have saved many lives from infections, the rise of antibiotic resistance has reduced their effectiveness. Before the advent of antibiotics, metals were used as antimicrobial agents. Metals and other inorganic materials exhibit broad-spectrum antimicrobial activity through mechanisms distinct from traditional antibiotics, and are capable of killing antibiotic-resistant strains. In this article, we review various inorganic antimicrobial materials and their mechanisms of action, and discuss potential strategies to combat antibiotic resistance.

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Publication Details

Journal
ACS Nano
Published
2026-04-07
DOI
https://doi.org/10.1021/acsnano.5c21363
Primary Topic
Antimicrobial agents and applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Inorganic Antimicrobial Materials

Yugen Zhang, Guangshun Yi, Jackie Y. Ying, Siew Ping Teong
ACS Nano
Antimicrobial agents and applications
article

Inorganic Antimicrobial Materials

Yugen Zhang, Guangshun Yi, Jackie Y. Ying, Siew Ping Teong
article en

Abstract

Infectious diseases caused by various pathogens pose a major threat throughout human history. While antibiotics have saved many lives from infections, the rise of antibiotic resistance has reduced their effectiveness. Before the advent of antibiotics, metals were used as antimicrobial agents. Metals and other inorganic materials exhibit broad-spectrum antimicrobial activity through mechanisms distinct from traditional antibiotics, and are capable of killing antibiotic-resistant strains. In this article, we review various inorganic antimicrobial materials and their mechanisms of action, and discuss potential strategies to combat antibiotic resistance.

ACS NanoVol. 20(15)
Agency for Science, Technology and Research (SG), King Faisal Specialist Hospital & Research Centre (SA), Institute for Sustainability (GB)
National Research Foundation Singapore, King Faisal Specialist Hospital and Research Centre
Openalex Percentile: Top 30%
Antimicrobial agents and applications
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