The AUTACE That Degrades KRAS and Engages CD8 <sup>+</sup> T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

T-cell recruitment and amplifying antitumor responses. Thus, AUTACE represents a promising strategy for the treatment of KRAS/TP53 co-mutant tumors.

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Publication Details

Journal
Advanced Science
Published
2026-04-07
DOI
https://doi.org/10.1002/advs.202518455
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00

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article

The AUTACE That Degrades KRAS and Engages CD8 + T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Chang Li, Ying Tang, Bo Pang, Bing Li et al.
Advanced Science
CAR-T cell therapy research
article

The AUTACE That Degrades KRAS and Engages CD8 + T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Chang Li, Ying Tang, Bo Pang, Bing Li, Yanan Hao, Pan Li
article en

Abstract

T-cell recruitment and amplifying antitumor responses. Thus, AUTACE represents a promising strategy for the treatment of KRAS/TP53 co-mutant tumors.

Advanced Science
Chongqing Maternal and Child Health Hospital (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
China Postdoctoral Science Foundation, Natural Science Foundation of Chongqing, Chongqing Municipal Education Commission
Good health and well-being
Openalex Percentile: Top 22%
CAR-T cell therapy research
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