A comparative analysis of safety and short-term efficacy between open and laparoscopic pancreaticoduodenectomy utilizing different drainage techniques

Purpose: To evaluate the safety profiles of open pancreaticoduodenectomy (OPD) and laparoscopic pancreaticoduodenectomy (LPD), and to analyze the respective advantages and disadvantages of various internal and external drainage techniques. Methods: All 260 patients successfully underwent laparoscopic or open PD. They were divided into laparoscopy and laparotomy groups by surgical approach, and into internal and external drainage groups by drainage method. Four subgroups were then formed: minimally invasive surgical internal drainage (MIS-ID) and minimally invasive surgical external drainage (MIS-ED), open surgical internal surgical drainage (OS-ID) and open surgical external drainage (OS-ED). Perioperative outcomes were compared across all groups and subgroups. Results: > 0.05). Conclusion: LPD can be performed safely and effectively without increasing postoperative complications compared to OPD. During LPD, the choice between internal and external drainage does not significantly influence outcomes following PD. Overall, LPD represents a safe and effective surgical approach, demonstrating significant potential for widespread adoption and clinical application.