Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High‐Accuracy Breeding Value Prediction Without Compromising Embryo Survival

guaranteeing > 90% genotype call rates. By preventing oversampling in small embryos and undersampling across embryo sizes, this diameter-guided control improves both embryo survival and GEBV prediction accuracy. This study provides a validated technical pathway for EGS that addresses the major practical bottleneck in livestock breeding. By ensuring reliable selection without compromising developmental potential, our work facilitates the rapid introgression of superior genetics and marks a significant step toward making EGS scalable, accelerating genetic progress in cattle and other species.

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Publication Details

Journal
The FASEB Journal
Published
2026-04-07
DOI
https://doi.org/10.1096/fj.202505089r
Primary Topic
Genetic and phenotypic traits in livestock
Type
article
Field-Weighted Citation Impact
0.00

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article

Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High‐Accuracy Breeding Value Prediction Without Compromising Embryo Survival

Lei An, Boxi Ye, Jingyu Zhang, Shuai Liu et al.
The FASEB Journal
Genetic and phenotypic traits in livestock
article

Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High‐Accuracy Breeding Value Prediction Without Compromising Embryo Survival

Lei An, Boxi Ye, Jingyu Zhang, Shuai Liu, Hang Shen, Jianhui Tian, Qin Zhang, Yubing Wang, Mengmeng Zhao, Jun Teng, Zhize Liu
article en

Abstract

guaranteeing > 90% genotype call rates. By preventing oversampling in small embryos and undersampling across embryo sizes, this diameter-guided control improves both embryo survival and GEBV prediction accuracy. This study provides a validated technical pathway for EGS that addresses the major practical bottleneck in livestock breeding. By ensuring reliable selection without compromising developmental potential, our work facilitates the rapid introgression of superior genetics and marks a significant step toward making EGS scalable, accelerating genetic progress in cattle and other species.

The FASEB JournalVol. 40(7)
Ministry of Agriculture (ID), Ministry of Agriculture and Rural Affairs (CN), Shandong Agricultural University (CN)
National Science and Technology Major Project, Chinese Universities Scientific Fund
Openalex Percentile: Top 20%
Genetic and phenotypic traits in livestock
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