Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High‐Accuracy Breeding Value Prediction Without Compromising Embryo Survival
guaranteeing > 90% genotype call rates. By preventing oversampling in small embryos and undersampling across embryo sizes, this diameter-guided control improves both embryo survival and GEBV prediction accuracy. This study provides a validated technical pathway for EGS that addresses the major practical bottleneck in livestock breeding. By ensuring reliable selection without compromising developmental potential, our work facilitates the rapid introgression of superior genetics and marks a significant step toward making EGS scalable, accelerating genetic progress in cattle and other species.
Authors
- Lei An (ORCID: https://orcid.org/0000-0001-8509-2466)
- Boxi Ye (ORCID: https://orcid.org/0009-0009-3178-2264)
- Jingyu Zhang (ORCID: https://orcid.org/0000-0001-8082-2650)
- Shuai Liu (ORCID: https://orcid.org/0000-0002-0699-2296)
- Hang Shen
- Jianhui Tian
- Qin Zhang
- Yubing Wang
- Mengmeng Zhao
- Jun Teng
- Zhize Liu
Institutions
- Ministry of Agriculture (ID)
- Ministry of Agriculture and Rural Affairs (CN)
- Shandong Agricultural University (CN)
Publication Details
- Journal
- The FASEB Journal
- Published
- 2026-04-07
- DOI
- https://doi.org/10.1096/fj.202505089r
- Primary Topic
- Genetic and phenotypic traits in livestock
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science and Technology Major Project
- Chinese Universities Scientific Fund