Isolated parenchymal cysts associated with a secretory meningioma: illustrative case

BACKGROUND: Meningiomas represent one of the most common intracranial tumors found in adults. Uncommonly, these tumors can be associated with an adjacent cyst, which is in direct contact with the tumor. Tumor location and source have previously been categorized into five subtypes. OBSERVATIONS: This report details the novel findings of a secretory meningioma with associated cysts separated from the tumor by brain parenchyma. Histopathological analysis of the cyst wall showed no evidence of neoplasia, suggesting the etiology to be from the parenchymal edema. LESSONS: The authors suggest that the presence of isolated cysts in conjunction with a meningioma (in this case a secretory meningioma) represents a new type VI cyst. These cysts are nonneoplastic and do not require direct operative access for control but can be managed, if needed, with simple aspiration. https://thejns.org/doi/10.3171/CASE25964.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2026-04-06
DOI
https://doi.org/10.3171/case25964
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Isolated parenchymal cysts associated with a secretory meningioma: illustrative case

Brett Simmons, Chun‐Chieh Lin, Nathan E. Simmons
Journal of Neurosurgery Case Lessons
Meningioma and schwannoma management
article

Isolated parenchymal cysts associated with a secretory meningioma: illustrative case

Brett Simmons, Chun‐Chieh Lin, Nathan E. Simmons
article en

Abstract

BACKGROUND: Meningiomas represent one of the most common intracranial tumors found in adults. Uncommonly, these tumors can be associated with an adjacent cyst, which is in direct contact with the tumor. Tumor location and source have previously been categorized into five subtypes. OBSERVATIONS: This report details the novel findings of a secretory meningioma with associated cysts separated from the tumor by brain parenchyma. Histopathological analysis of the cyst wall showed no evidence of neoplasia, suggesting the etiology to be from the parenchymal edema. LESSONS: The authors suggest that the presence of isolated cysts in conjunction with a meningioma (in this case a secretory meningioma) represents a new type VI cyst. These cysts are nonneoplastic and do not require direct operative access for control but can be managed, if needed, with simple aspiration. https://thejns.org/doi/10.3171/CASE25964.

Journal of Neurosurgery Case LessonsVol. 11(14)
Dartmouth College (US), Dartmouth–Hitchcock Medical Center (US), Dartmouth Psychiatric Research Center (US)
Openalex Percentile: Top 22%
Meningioma and schwannoma management
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