Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control
) over 3 months and high flexural strength (> 80 MPa). Antibiofilm activity and biosafety are further confirmed in an in vivo rat tooth-restoration model. This dual-antibacterial, bisilanized RBC offers promising clinical opportunities to durably restore teeth by effectively controlling biofilm, preventing caries recurrence, and reducing the risk of periodontal infections. The technology holds great potential for advancing restorative dentistry and promoting oral health.
Authors
- Naiera Zayed (ORCID: https://orcid.org/0000-0002-7773-8199)
- Jelle Verdonck (ORCID: https://orcid.org/0000-0002-4105-5126)
- K. Van Landuyt
- Wim Teughels (ORCID: https://orcid.org/0000-0001-7675-5643)
- Lingyue Liu (ORCID: https://orcid.org/0000-0002-5000-1605)
- Shengjie Liang
- Mehraveh Saghi (ORCID: https://orcid.org/0009-0006-8804-1529)
- Line Etiennot (ORCID: https://orcid.org/0000-0002-2777-0967)
- Fei Zhang
- Chenmin Yao
- C. Huang
- Bart Van Meerbeek
Institutions
- Wuhan University (CN)
- Stomatology Hospital (CN)
- Department of Public Health (MM)
- Department of Public Health (US)
- KU Leuven (BE)
Publication Details
- Journal
- Advanced Science
- Published
- 2026-04-07
- DOI
- https://doi.org/10.1002/advs.75146
- Primary Topic
- Dental materials and restorations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities