Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c <sup>+</sup> Basal Cells in Severe Lung Injury
basal cell population. Together, these findings identify ERBB4 signaling as a critical regulator that constrains pathological epithelial remodeling during severe lung injury.
Authors
- Shenfei Sun (ORCID: https://orcid.org/0000-0002-5034-4333)
- Xinran Deng (ORCID: https://orcid.org/0000-0002-9024-4337)
- Yamei Jiang (ORCID: https://orcid.org/0000-0002-7709-7328)
- Kaijun Lin
- Xinhua Lin (ORCID: https://orcid.org/0000-0003-1371-9850)
- Haonan Wang (ORCID: https://orcid.org/0000-0003-3590-7633)
- Jian Sun (ORCID: https://orcid.org/0000-0003-0067-5967)
- Li Yan Yuan (ORCID: https://orcid.org/0000-0002-7144-9441)
- Zhenju Song
- Hailin Ding
- Yu Wang
- Ming Ye
Institutions
- Fudan University (CN)
- Inner Mongolia University (CN)
- Zhongshan Hospital (CN)
- Precision Research (United States) (US)
- Children's Hospital of Fudan University (CN)
Publication Details
- Journal
- Advanced Science
- Published
- 2026-04-07
- DOI
- https://doi.org/10.1002/advs.202519151
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China
- National Major Science and Technology Projects of China