Symptomatic Methemoglobinemia at Low Levels in a Patient With Obstructive Sleep Apnea

Previously reported cases of hypoxemia secondary to methemoglobinemia usually had measured methemoglobin percentages of around 20% or greater. We report an unusual case of methemoglobinemia secondary to dapsone use in a 66-year-old man with obstructive sleep apnea who presented with dyspnea and hypoxia with a methemoglobin percentage of less than 10%.

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Publication Details

Journal
Annals of Internal Medicine Clinical Cases
Published
2026-04-01
DOI
https://doi.org/10.7326/aimcc.2025.1176
Primary Topic
Methemoglobinemia and Tumor Lysis Syndrome
Type
article
Field-Weighted Citation Impact
0.00
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article

Symptomatic Methemoglobinemia at Low Levels in a Patient With Obstructive Sleep Apnea

Don Mathew, Rachel E. Powell
Annals of Internal Medicine Clinical Cases
Methemoglobinemia and Tumor Lysis Syndrome
article

Symptomatic Methemoglobinemia at Low Levels in a Patient With Obstructive Sleep Apnea

Don Mathew, Rachel E. Powell
article en

Abstract

Previously reported cases of hypoxemia secondary to methemoglobinemia usually had measured methemoglobin percentages of around 20% or greater. We report an unusual case of methemoglobinemia secondary to dapsone use in a 66-year-old man with obstructive sleep apnea who presented with dyspnea and hypoxia with a methemoglobin percentage of less than 10%.

Annals of Internal Medicine Clinical CasesVol. 5(4)
University of Pittsburgh (US), University of Pittsburgh Medical Center (US)
Good health and well-being
Openalex Percentile: Top 29%
Methemoglobinemia and Tumor Lysis Syndrome
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