Investigation of the Prevalence of Associated Genetic Mutations (Co-Mutations) in Patients with Actionable Driver Mutations in Lung Cancer: A Retrospective Study

: By constructing clusters based on the aggregate of genomic alterations in patients with actionable mutations, it is possible to predict associations with distinct demographic and clinical characteristics. Future research should apply this analytical approach to larger cohorts to further characterize these subgroups and investigate potential correlations with therapeutic efficacy.

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Publication Details

Journal
Diagnostics
Published
2026-04-07
DOI
https://doi.org/10.3390/diagnostics16071106
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Investigation of the Prevalence of Associated Genetic Mutations (Co-Mutations) in Patients with Actionable Driver Mutations in Lung Cancer: A Retrospective Study

Leonard Saiegh, Salam Mazareb, Edmond Sabo, Abed Agbarya et al.
Diagnostics
Lung Cancer Treatments and Mutations
article

Investigation of the Prevalence of Associated Genetic Mutations (Co-Mutations) in Patients with Actionable Driver Mutations in Lung Cancer: A Retrospective Study

Leonard Saiegh, Salam Mazareb, Edmond Sabo, Abed Agbarya, Kamel Mhameed, Walid Shalata, Dan Levy Faber, Haitam Nasrallah, Mohammad Sheikh-Ahmad, Yuval Shaham
article en

Abstract

: By constructing clusters based on the aggregate of genomic alterations in patients with actionable mutations, it is possible to predict associations with distinct demographic and clinical characteristics. Future research should apply this analytical approach to larger cohorts to further characterize these subgroups and investigate potential correlations with therapeutic efficacy.

DiagnosticsVol. 16(7)
Ben-Gurion University of the Negev (IL), Technion – Israel Institute of Technology (IL), Soroka Medical Center (IL), Rambam Health Care Campus (IL), Bnai Zion Medical Center (IL), Carmel Medical Center (IL), Rappaport Family Institute for Research in the Medical Sciences (IL)
Good health and well-being
Openalex Percentile: Top 29%
Lung Cancer Treatments and Mutations
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