A stalactite-inspired NIR/pH-responsive visualizable nano-platform for microenvironment-activated therapy of peri-implantitis-induced bone defects
, using a rat peri-implantitis model, CIMA facilitated bone regeneration within the inflamed peri-implant region. Collectively, this artificially engineered, stalactite-inspired CIMA system promoted bone regeneration and provided combined anti-inflammatory and antibacterial functions, offering a promising strategy for treating peri-implantitis.
Authors
- Zixun Lan (ORCID: https://orcid.org/0000-0003-1374-3818)
- Jiahui Yang
- Lan Liao
- Xiaolei Wang
- Yifan Cai
- Qiaowen Zheng
- Ziyu Zhou
- Xianglin Dai
- Yingying Xu
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Education Department of Jiangxi Province (CN)
- Nanchang Center for Disease Control and Prevention (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Bioactive Materials
- Published
- 2026-04-07
- DOI
- https://doi.org/10.1016/j.bioactmat.2026.03.005
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Nanchang University
- Jiangxi Provincial Department of Science and Technology
- Jiangsu Provincial Key Research and Development Program