Volumetric Scattering Microscopy
embryos, achieving preserved spatial resolution, enhanced optical sectioning, and quantitative accuracy under strong scattering conditions. VSM supports large-field, robust volumetric imaging in both layered and fully embedded scattering environments. By transforming scattered light into a structured encoding resource, VSM establishes a scalable pathway toward routine three-dimensional fluorescence imaging in complex biological systems.
Authors
- Wenhao Liu
- Xuanwen Hua (ORCID: https://orcid.org/0000-0002-5946-0808)
- Hongmanlin Zhang (ORCID: https://orcid.org/0000-0001-6051-9742)
- Shuyi Nie (ORCID: https://orcid.org/0000-0002-0495-7104)
- Edward A. Botchwey (ORCID: https://orcid.org/0000-0003-1140-5786)
- Shu Jia
- Zijun Gao
- Keyi Han
- Zhi Ling
Institutions
- Georgia Institute of Technology (US)
- The Wallace H. Coulter Department of Biomedical Engineering (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-07
- DOI
- https://doi.org/10.64898/2026.04.03.716429
- Primary Topic
- Random lasers and scattering media
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health