Functional analysis of type VII secretion system links to host immune evasion mechanism in Mycobacterium tuberculosis

requires ESX-4. Therefore, the type VII secretion system of ESX-associated genes plays a crucial role in bacterial survival and action against autophagosome-lysosome fusion. Thus, studying this system will explore the effects of specific antigenic structures and their relationships with autophagy and mycobacterial self-defense mechanisms.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2026-04-07
DOI
https://doi.org/10.3389/fcimb.2026.1797994
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Functional analysis of type VII secretion system links to host immune evasion mechanism in Mycobacterium tuberculosis

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Functional analysis of type VII secretion system links to host immune evasion mechanism in Mycobacterium tuberculosis

Uma Devi Ranganathan, Ramalingam Bethunaickan, Venkataraman Prabhu, Madhavan Dhanapal, Karthikeyan Sundaram, Sridhar Rathinam
article en

Abstract

requires ESX-4. Therefore, the type VII secretion system of ESX-associated genes plays a crucial role in bacterial survival and action against autophagosome-lysosome fusion. Thus, studying this system will explore the effects of specific antigenic structures and their relationships with autophagy and mycobacterial self-defense mechanisms.

Frontiers in Cellular and Infection MicrobiologyVol. 16
SRM Institute of Science and Technology (IN), Chettinad Academy of Research and Education (IN), Indian Council of Medical Research (IN)
Openalex Percentile: Top 26%
Tuberculosis Research and Epidemiology
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