Receptor subtype distribution from PET occupancy studies: Novel analysis of maximum occupancy images using a selective drug and a non-selective tracer
ratio (1.50-2.41). In general, our approach allows estimation when occupancy studies are performed with a selective drug and a non-selective tracer.
Authors
- Eugenii A. Rabiner (ORCID: https://orcid.org/0000-0003-3612-6687)
- Jocelyn Hoye (ORCID: https://orcid.org/0000-0003-1404-5085)
- Cristian Constantinescu (ORCID: https://orcid.org/0000-0001-5709-9476)
- Alaaddin Ibrahimy (ORCID: https://orcid.org/0000-0003-2358-9260)
- Mark Slifstein (ORCID: https://orcid.org/0000-0003-2142-6353)
- Graham E Searle
- Evan D Morris
Institutions
- Yale University (US)
- Mitsubishi Corporation (United Kingdom) (GB)
- Perceptive Engineering (United Kingdom) (GB)
- Stony Brook University (US)
Publication Details
- Journal
- Journal of Cerebral Blood Flow & Metabolism
- Published
- 2026-04-07
- DOI
- https://doi.org/10.1177/0271678x261438226
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer
- Yale University
- National Institutes of Health