A multi-centre quality improvement project to assess the impact of a standardised NIV care bundle on mortality outcomes in patients with acute type 2 respiratory failure

The evidence for non-invasive ventilation (NIV) is clear; however, real-world outcomes fall short of those demonstrated by clinical trials. We developed a five-step care bundle in line with BTS quality standards to standardise management and guide clinicians through the first few hours of NIV care. This was combined with staff training initiatives. The project aimed to reduce acute NIV mortality to 10%. Although this target was not met, the project delivered a 7% reduction in mortality from 28% to 21%, equating to 143 fewer deaths in 2023 compared to 2022. The project also delivered increased staff confidence. Through this project we have demonstrated that early, effective NIV, in appropriate patients, delivered in a standardised way by confident and competent staff, improves outcomes.

Authors

Institutions

Publication Details

Journal
Clinical Medicine
Published
2026-04-07
DOI
https://doi.org/10.1016/j.clinme.2026.100574
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A multi-centre quality improvement project to assess the impact of a standardised NIV care bundle on mortality outcomes in patients with acute type 2 respiratory failure

MC Juniper, R.H. Mason, CJ Michie, KR Ward et al.
Clinical Medicine
Sepsis Diagnosis and Treatment
article

A multi-centre quality improvement project to assess the impact of a standardised NIV care bundle on mortality outcomes in patients with acute type 2 respiratory failure

MC Juniper, R.H. Mason, CJ Michie, KR Ward, S Beresford, PW Creber
article en

Abstract

The evidence for non-invasive ventilation (NIV) is clear; however, real-world outcomes fall short of those demonstrated by clinical trials. We developed a five-step care bundle in line with BTS quality standards to standardise management and guide clinicians through the first few hours of NIV care. This was combined with staff training initiatives. The project aimed to reduce acute NIV mortality to 10%. Although this target was not met, the project delivered a 7% reduction in mortality from 28% to 21%, equating to 143 fewer deaths in 2023 compared to 2022. The project also delivered increased staff confidence. Through this project we have demonstrated that early, effective NIV, in appropriate patients, delivered in a standardised way by confident and competent staff, improves outcomes.

Clinical MedicineVol. 26(3)
North Bristol NHS Trust (GB), Royal United Hospital (GB), Southmead Hospital (GB), Great Western Hospital (GB), NHS Digital (GB), Royal United Hospital Bath NHS Trust (GB)
Good health and well-being
Openalex Percentile: Top 34%
Sepsis Diagnosis and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.