Sugammadex reversal of an accidental rocuronium overdose in a dog in the context of incivility in the workplace

IV) was administered 390 minutes after the constant-rate infusion of rocuronium was initiated (and 270 minutes after the infusion stopped), leading to return of spontaneous ventilation within one minute, without haemodynamic compromise. Tracheal extubation occurred uneventfully 60 minutes after injection of sugammadex. This report demonstrates that sugammadex can effectively reverse a large rocuronium overdose in dogs, providing a valuable rescue option in deep neuromuscular blockade. It also highlights the role of workplace incivility in contributing to medication error. The complex technical demands of veterinary anaesthesia, including medication preparation and delivery, are vulnerable to inadequate safety practices. Awareness of both pharmacological rescue strategies and the impact of incivility, alongside implementing standard operating procedures aimed at reducing medication error, are essential to improving patient outcomes in veterinary anaesthesia.

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Publication Details

Journal
Veterinary Anaesthesia and Analgesia
Published
2026-04-07
DOI
https://doi.org/10.1016/j.vaa.2026.101229
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00
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article

Sugammadex reversal of an accidental rocuronium overdose in a dog in the context of incivility in the workplace

Verónica Salazar Nussio, Sabina Díez Bernal
Veterinary Anaesthesia and Analgesia
Anesthesia and Sedative Agents
article

Sugammadex reversal of an accidental rocuronium overdose in a dog in the context of incivility in the workplace

Verónica Salazar Nussio, Sabina Díez Bernal
article en

Abstract

IV) was administered 390 minutes after the constant-rate infusion of rocuronium was initiated (and 270 minutes after the infusion stopped), leading to return of spontaneous ventilation within one minute, without haemodynamic compromise. Tracheal extubation occurred uneventfully 60 minutes after injection of sugammadex. This report demonstrates that sugammadex can effectively reverse a large rocuronium overdose in dogs, providing a valuable rescue option in deep neuromuscular blockade. It also highlights the role of workplace incivility in contributing to medication error. The complex technical demands of veterinary anaesthesia, including medication preparation and delivery, are vulnerable to inadequate safety practices. Awareness of both pharmacological rescue strategies and the impact of incivility, alongside implementing standard operating procedures aimed at reducing medication error, are essential to improving patient outcomes in veterinary anaesthesia.

Veterinary Anaesthesia and AnalgesiaVol. 53(4)
Roslin Institute (GB), Universidad Alfonso X el Sabio (ES), University of Edinburgh (GB)
Openalex Percentile: Top 33%
Anesthesia and Sedative Agents
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