Cannabidiol prevents mucosal HIV-1 transmission by targeting Langerhans cells, dendritic cells, macrophages and T-cells

T-cells infection. Altogether, CBD inhibits infection of all HIV-1 cellular targets, and commercial CBD products might be repositioned as novel HIV-1 pre-exposure prophylaxis, namely 'CBD PrEP'.

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Publication Details

Journal
Mucosal Immunology
Published
2026-04-01
DOI
https://doi.org/10.1016/j.mucimm.2026.03.006
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Cannabidiol prevents mucosal HIV-1 transmission by targeting Langerhans cells, dendritic cells, macrophages and T-cells

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Mucosal Immunology
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Cannabidiol prevents mucosal HIV-1 transmission by targeting Langerhans cells, dendritic cells, macrophages and T-cells

Yonatan Ganor, Morgane Bomsel, Marc Zerbib, Daniela Cota, Jammy Mariotton, Nicolas Barry Delongchamps, Hugo Génin, I. Matias, Caio César Barbosa Bomfim
article en

Abstract

T-cells infection. Altogether, CBD inhibits infection of all HIV-1 cellular targets, and commercial CBD products might be repositioned as novel HIV-1 pre-exposure prophylaxis, namely 'CBD PrEP'.

Mucosal Immunology
Centre National de la Recherche Scientifique (FR), Université de Bordeaux (FR), Inserm (FR), Université Paris Cité (FR), Neurocentre Magendie (FR), Institut Cochin (FR), Hôpital Saint-Vincent-de-Paul (FR)
Sidaction, Institut National de la Santé et de la Recherche Médicale, Université de Bordeaux
Good health and well-being
Openalex Percentile: Top 30%
Cannabis and Cannabinoid Research
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