Fusogenic Liposome-Mediated Extracellular Vesicles MicroRNA Profiling for Lung Cancer Diagnosis
= 141), the profiled signature enabled early diagnosis, therapy monitoring, and prognosis evaluation with an accuracy of up to 93.1%. The platform streamlines the diagnostic workflow into a single fusogenic step, providing an RNA extraction-free and proof-of-concept liquid biopsy framework for potential LC management.
Authors
- Rui Wang (ORCID: https://orcid.org/0000-0003-0773-2127)
- Zhengying Gu (ORCID: https://orcid.org/0000-0002-8597-6752)
- Xvelian Li
- Minjia Niu
- Yuewei Zhao
- Fanyu Meng (ORCID: https://orcid.org/0009-0004-3587-4151)
- Wei Nie (ORCID: https://orcid.org/0000-0001-9899-1428)
- Chen Chi
- H. Zhong
- Lin Huang
- Yuqing Lou
- Jiayi Wang
- Yan Zhou
- Yujie Wang
- Wenjun Yu
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Chest Hospital (CN)
- Shanghai Cancer Institute (CN)
Publication Details
- Journal
- ACS Nano
- Published
- 2026-04-07
- DOI
- https://doi.org/10.1021/acsnano.6c00879
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- National Key Research and Development Program of China