Chemical Characterization, Evaluation of Antimicrobial Potential, and Cytotoxic Activity of Thuja occidentalis L. and Myrtus communis L. Essential Oils for Topical Applications
, with EOs extracted from fresh leaves and cones exhibiting the lowest MICs (1.95-7.8 µL/mL). All EOs did not show cytotoxicity to human keratinocytes at concentrations ≤125 µg/mL and, when diluted to 0.05%, indicated excellent skin compatibility in human patch tests. This study suggests that myrtle and thuja EOs, particularly myrtle, are promising and safe natural antimicrobial agents for dermatological and cosmetic formulations.
Authors
- Nafi̇z Çeli̇ktaş (ORCID: https://orcid.org/0000-0002-0467-1034)
- Irina Titorencu (ORCID: https://orcid.org/0000-0001-9312-5811)
- Vlad Andrei Neacșu (ORCID: https://orcid.org/0000-0003-2254-0799)
- Durmuş Alpaslan Kaya
- Elena Dănilă
- Mădalina Albu Kaya
- Ioana Cristina Marinas
- Minodora Maria Marin
- Raluca Țuțuianu
- Madalina Diana Gaboreanu
Institutions
- University of Bucharest (RO)
- National Research & Development Institute for Textiles and Leather (RO)
- Mustafa Kemal University (TR)
- Universitatea Națională de Știință și Tehnologie Politehnica București (RO)
Publication Details
- Journal
- Molecules
- Published
- 2026-04-07
- DOI
- https://doi.org/10.3390/molecules31071225
- Primary Topic
- Essential Oils and Antimicrobial Activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Academia Româna
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii