Emergence of a carbapenem-resistant Klebsiella pneumoniae ST15-KL19 clone with elevated virulence potential in a tertiary hospital in China

Introduction: strains. Among these, ST15 is an expanding global high-risk clone, yet variants with elevated virulence potential carrying the KL19 capsular type remain rarely reported. Methods: ST15-KL19 clone exhibiting elevated virulence potential, isolated from a tertiary hospital in eastern China. Results: gene was located within a stable composite transposon, suggesting efficient mobility and long-term maintenance. Phylogenetic analysis demonstrated that the isolates were closely related to other Chinese ST15-KL19 strains, indicating recent clonal expansion and local dissemination. Discussion: lineages.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2026-04-07
DOI
https://doi.org/10.3389/fcimb.2026.1745492
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Emergence of a carbapenem-resistant Klebsiella pneumoniae ST15-KL19 clone with elevated virulence potential in a tertiary hospital in China

Yujing Zhang, Guiling Li, Chuanli Ren, Guqi Ren et al.
Frontiers in Cellular and Infection Microbiology
Antibiotic Resistance in Bacteria
article

Emergence of a carbapenem-resistant Klebsiella pneumoniae ST15-KL19 clone with elevated virulence potential in a tertiary hospital in China

Yujing Zhang, Guiling Li, Chuanli Ren, Guqi Ren, Longlong Tian, Xinan Jiao
article en

Abstract

Introduction: strains. Among these, ST15 is an expanding global high-risk clone, yet variants with elevated virulence potential carrying the KL19 capsular type remain rarely reported. Methods: ST15-KL19 clone exhibiting elevated virulence potential, isolated from a tertiary hospital in eastern China. Results: gene was located within a stable composite transposon, suggesting efficient mobility and long-term maintenance. Phylogenetic analysis demonstrated that the isolates were closely related to other Chinese ST15-KL19 strains, indicating recent clonal expansion and local dissemination. Discussion: lineages.

Frontiers in Cellular and Infection MicrobiologyVol. 16
Northern Jiangsu People's Hospital (CN), Ministry of Agriculture and Rural Affairs (CN), Yangzhou University (CN)
Good health and well-being
Openalex Percentile: Top 33%
Antibiotic Resistance in Bacteria
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