Emergence of a carbapenem-resistant Klebsiella pneumoniae ST15-KL19 clone with elevated virulence potential in a tertiary hospital in China
Introduction: strains. Among these, ST15 is an expanding global high-risk clone, yet variants with elevated virulence potential carrying the KL19 capsular type remain rarely reported. Methods: ST15-KL19 clone exhibiting elevated virulence potential, isolated from a tertiary hospital in eastern China. Results: gene was located within a stable composite transposon, suggesting efficient mobility and long-term maintenance. Phylogenetic analysis demonstrated that the isolates were closely related to other Chinese ST15-KL19 strains, indicating recent clonal expansion and local dissemination. Discussion: lineages.
Authors
- Yujing Zhang (ORCID: https://orcid.org/0000-0002-5207-1762)
- Guiling Li
- Chuanli Ren
- Guqi Ren
- Longlong Tian
- Xinan Jiao
Institutions
- Northern Jiangsu People's Hospital (CN)
- Ministry of Agriculture and Rural Affairs (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-04-07
- DOI
- https://doi.org/10.3389/fcimb.2026.1745492
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00