Dual Remission in Patients with Moderate-to-Severe Asthma and CRSwNP Treated with Dupilumab: A 24-Month Real-World Study

Dupilumab is highly effective, enabling 88% of patients to achieve Dual Remission after 24 months. However, full olfactory restitution is distinct from structural polyp regression and harder to achieve, likely due to persistent neuroepithelial damage.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-07
DOI
https://doi.org/10.3390/jcm15072787
Primary Topic
Sinusitis and nasal conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Dual Remission in Patients with Moderate-to-Severe Asthma and CRSwNP Treated with Dupilumab: A 24-Month Real-World Study

Alvise Berti, Walter Cestaro, Francesco Menzella, F Gialdini et al.
Journal of Clinical Medicine
Sinusitis and nasal conditions
article

Dual Remission in Patients with Moderate-to-Severe Asthma and CRSwNP Treated with Dupilumab: A 24-Month Real-World Study

Alvise Berti, Walter Cestaro, Francesco Menzella, F Gialdini, Annamaria Bosi, Tatiana Scandiuzzi Piovesan, Sara Munari, Eugenio De Corso, Marcello Cottini, Lorenzo Corsi, Carlo Lombardi
article en

Abstract

Dupilumab is highly effective, enabling 88% of patients to achieve Dual Remission after 24 months. However, full olfactory restitution is distinct from structural polyp regression and harder to achieve, likely due to persistent neuroepithelial damage.

Journal of Clinical MedicineVol. 15(7)
University of Bergamo (IT), University of Trento (IT), University of Perugia (IT), Ospedale Santa Chiara (IT), AULSS 2 Marca Trevigiana (IT), Presidio Ospedaliero (IT), Fondazione Poliambulanza Istituto Ospedaliero (IT)
Openalex Percentile: Top 27%
Sinusitis and nasal conditions
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