Multidisciplinary treatment of giant perianal condyloma acuminatum (Buschke-Lowenstein tumor) – A case report

Giant condyloma acuminatum (GCA) is a highly morbid, rare, and difficult to treat clinical entity. It is a locally invasive tumour of the anogenital region that is classified as between condyloma and squamous cell carcinoma. Treatment requires radical surgical resection and, given the location of the tumor, often requires complex reconstruction. The present case represents an extreme example of this condition and highlights the need for excellent, coordinated, long-term multidisciplinary care to achieve an optimal outcome for patients affected for this pathology.

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Publication Details

Journal
Surgery Case Reports
Published
2026-04-07
DOI
https://doi.org/10.1016/j.sycrs.2026.100202
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Multidisciplinary treatment of giant perianal condyloma acuminatum (Buschke-Lowenstein tumor) – A case report

Molly M. Ford, Phillip J. Williams
Surgery Case Reports
Cervical Cancer and HPV Research
article

Multidisciplinary treatment of giant perianal condyloma acuminatum (Buschke-Lowenstein tumor) – A case report

Molly M. Ford, Phillip J. Williams
article en

Abstract

Giant condyloma acuminatum (GCA) is a highly morbid, rare, and difficult to treat clinical entity. It is a locally invasive tumour of the anogenital region that is classified as between condyloma and squamous cell carcinoma. Treatment requires radical surgical resection and, given the location of the tumor, often requires complex reconstruction. The present case represents an extreme example of this condition and highlights the need for excellent, coordinated, long-term multidisciplinary care to achieve an optimal outcome for patients affected for this pathology.

Surgery Case ReportsVol. 8
Vanderbilt University Medical Center (US)
Openalex Percentile: Top 28%
Cervical Cancer and HPV Research
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