Long-Term Outcomes of Low-Dose-Rate Brachytherapy in Localized Prostate Cancer: A 17-Year Retrospective Analysis of a Single-Center Portuguese Cohort

: BT is an effective treatment in localized prostate cancer patients, with comparable outcomes and consistent with the OS and BRFS rates reported in the current literature for radical prostatectomy and external beam radiotherapy approaches, and with a reduced frequency of complications. PSA serum levels > 20 ng/mL, GS ≥ 8 and cT stage ≥ T2c can be used as strong predictors of death and/or biochemical recurrence during patients' follow-up.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-07
DOI
https://doi.org/10.3390/jcm15072778
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Long-Term Outcomes of Low-Dose-Rate Brachytherapy in Localized Prostate Cancer: A 17-Year Retrospective Analysis of a Single-Center Portuguese Cohort

Carlos Rabaça, Domingos Sanchez Roda, Amílcar Sismeiro, Ricardo Godinho et al.
Journal of Clinical Medicine
Prostate Cancer Diagnosis and Treatment
article

Long-Term Outcomes of Low-Dose-Rate Brachytherapy in Localized Prostate Cancer: A 17-Year Retrospective Analysis of a Single-Center Portuguese Cohort

Carlos Rabaça, Domingos Sanchez Roda, Amílcar Sismeiro, Ricardo Godinho, Guy Antoine Vieira, Sofia Macedo, José Alberto Pereira, Bruno J. Pereira, Mário Lourenço, Margarida Regencio
article en

Abstract

: BT is an effective treatment in localized prostate cancer patients, with comparable outcomes and consistent with the OS and BRFS rates reported in the current literature for radical prostatectomy and external beam radiotherapy approaches, and with a reduced frequency of complications. PSA serum levels > 20 ng/mL, GS ≥ 8 and cT stage ≥ T2c can be used as strong predictors of death and/or biochemical recurrence during patients' follow-up.

Journal of Clinical MedicineVol. 15(7)
University of Beira Interior (PT), Instituto Superior Bissaya Barreto (PT), Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), Hospital da Luz (PT), Instituto Português de Oncologia de Coimbra Francisco Gentil (PT), University of Coimbra (PT)
Good health and well-being
Openalex Percentile: Top 28%
Prostate Cancer Diagnosis and Treatment
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