Whole-brain cellular-resolution functional network properties of seizure susceptibility
larvae and predicted individuals' seizure risk independently of their observable phenotype. These findings uncover the cellular-resolution network properties of a zebrafish model of Dravet syndrome and establish a predictive framework for seizure susceptibility grounded in multi-scale functional connectivity.
Authors
- Itia Amandine Favre-bulle
- Ellen J. Hoffman (ORCID: https://orcid.org/0000-0002-5083-1369)
- Jessica C. Beevis
- Maya Wilde (ORCID: https://orcid.org/0000-0002-5762-8427)
- Manxiu Ma (ORCID: https://orcid.org/0000-0003-1905-3615)
- Sarah J. Stednitz (ORCID: https://orcid.org/0000-0002-8223-1528)
- Andre D. H. Peterson (ORCID: https://orcid.org/0000-0001-9620-3475)
- Joshua Arnold
- Wei Qin
Institutions
- The University of Queensland (AU)
- The University of Melbourne (AU)
- Yale University (US)
- Czech Technical University in Prague (CZ)
- Monash University (AU)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-07
- DOI
- https://doi.org/10.64898/2026.04.04.715761
- Primary Topic
- Zebrafish Biomedical Research Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Australian Research Council
- National Health and Medical Research Council
- National Institute of Neurological Disorders and Stroke