Rapid Methadone Titration for Opioid Withdrawal Management

This Teachable Moment describes how traditional titration protocols for patients with fentanyl use disorder may be inadequate for patients with frequent, high-dose, or high-potency opioid use.

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Publication Details

Journal
JAMA Internal Medicine
Published
2026-04-06
DOI
https://doi.org/10.1001/jamainternmed.2026.0354
Primary Topic
Pain Management and Opioid Use
Type
article
Field-Weighted Citation Impact
0.00
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article

Rapid Methadone Titration for Opioid Withdrawal Management

Gregory T. Woods, William C. Oles
JAMA Internal Medicine
Pain Management and Opioid Use
article

Rapid Methadone Titration for Opioid Withdrawal Management

Gregory T. Woods, William C. Oles
article en

Abstract

This Teachable Moment describes how traditional titration protocols for patients with fentanyl use disorder may be inadequate for patients with frequent, high-dose, or high-potency opioid use.

JAMA Internal Medicine
Brigham and Women's Hospital (US), University of California, San Francisco (US)
Openalex Percentile: Top 5%
Pain Management and Opioid Use
DOISourceOpenAlex
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Rapid Methadone Titration for Opioid Withdrawal Management — Gregory T. Woods, William C. Oles · JAMA Internal Medicine (2026) | TGRS Research Map | TGRS