Predicting Behavior of Cutaneous Head and Neck Squamous Cell Carcinoma in Transplant Recipients

Objective: Head/neck location and immunosuppression are independent risk factors related to cutaneous head and neck squamous cell carcinomas (cHNSCCs) in solid organ transplant recipients (SOTRs). Traditional staging criteria underperform in risk stratification. We aim to identify the utility of clinicopathologic factors for risk stratification of cHNSCCs in SOTRs. Study Design: Retrospective cohort study. Setting: Single tertiary center. Methods: -tests for age at transplant, age at first posttransplant cHNSCC, and overall lifespan; ANOVA for transplant type; and chi-square test for sex and ethnicity. Results: = .21). Conclusion: Deeply invasive cHNSCCs are associated with decreased overall survival in SOTRs. Age at transplant approaches significance for deep invasion. Data on immunosuppression and genetic analysis may further enhance prognostication.