Hydration-Mediated Energy Landscapes Govern Rotational Flexibility in Membrane-Bound Annexin V Assemblies
coordination. Our findings establish interfacial water as a key mediator of supramolecular organization and stabilization, proposing a mechanism for hydration-mediated conformational flexibility during Annexin-driven membrane repair.
Authors
- Kien Xuan Ngo (ORCID: https://orcid.org/0000-0002-9710-5452)
- Kazuki Miyata (ORCID: https://orcid.org/0000-0002-1641-2160)
- Ayhan Yurtsever (ORCID: https://orcid.org/0000-0003-3779-5196)
- Takashi Sumikama (ORCID: https://orcid.org/0000-0003-3696-5720)
- Haohui Zhang (ORCID: https://orcid.org/0000-0001-8432-3672)
- Takeshi Fukuma (ORCID: https://orcid.org/0000-0001-8971-6002)
- Hiroki Konno (ORCID: https://orcid.org/0000-0002-1712-171X)
- Shunsuke Mochizuki
- Kaito Hirata
- Ayaka Imamura
Institutions
- Kanazawa University (JP)
- Nagoya Institute of Technology (JP)
- Kyoto University (JP)
- Center for Nanoscale Science and Technology (US)
- Life Science Institute (JP)
- Healthwise (US)
- Living Systems (United States) (US)
- Frontier Aerospace Corporation (United States) (US)
Publication Details
- Journal
- Nano Letters
- Published
- 2026-04-06
- DOI
- https://doi.org/10.1021/acs.nanolett.6c00388
- Primary Topic
- Lipid Membrane Structure and Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Core Research for Evolutional Science and Technology
- Precursory Research for Embryonic Science and Technology