Bioinspired “liquid-solid” biphasic dressing with exudate-gating transport, defense-attack antibacterial activity, and anti-adhesion property for exuding infected wound therapy
. The same oil layer provides a low-adhesion interface, enabling nearly painless dressing changes with minimal peeling force. In an infected wound model, the dressing accelerates healing, suppresses inflammatory cytokine expression, and reduces bacterial burden. This "liquid-solid" strategy offers a promising paradigm for developing next-generation smart biomaterials for complex wound care.
Authors
- Malcolm M. Q. Xing (ORCID: https://orcid.org/0000-0002-3547-0462)
- Zizhao Chen (ORCID: https://orcid.org/0000-0002-3851-4803)
- Botao Song
- Mingzhang Li
- Yixuan Li
- Changming Wang
- Jiang Chang
- Hao Shen
- Chunsheng Guan
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Northwest University (CN)
- Shanghai Sixth People's Hospital (CN)
- University of Chinese Academy of Sciences (CN)
- University of Manitoba (CA)
Publication Details
- Journal
- Bioactive Materials
- Published
- 2026-04-06
- DOI
- https://doi.org/10.1016/j.bioactmat.2026.04.001
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China