Glandular Cells of Forest Musk Deer Autonomously Synthesize Sex Steroid Hormones
expression showing an upward trend. Elevated cholesterol increased several sex steroid hormone levels: pregnenolone, progesterone, 17α-hydroxypregnenolone, androstenedione, androsterone, and etiocholanolone by 4.12-, 1.46-, 33.42-, 2.06-, 3.11-, and 5.65-fold, respectively. These results collectively indicate that the musk glandular cells can synthesize sex steroid hormones de novo and suggest that cholesterol may regulate their biosynthesis in these cells.
Authors
- Yele Zhang (ORCID: https://orcid.org/0009-0004-8373-8728)
- Shuqiang Liu (ORCID: https://orcid.org/0000-0001-7227-3997)
- Congxue Yao
- Henghao Zhang
- Jingyao Hu
- Habib Bati
- Zexiu Zhang
- Rongzeng Tan
- Zhiyi Lou
- Xiangyu Han
- Xian An
- Xin Dou
- Yuetong Zhao
Institutions
- Beijing Forestry University (CN)
- Sino Biological (China) (CN)
Publication Details
- Journal
- Biology
- Published
- 2026-04-06
- DOI
- https://doi.org/10.3390/biology15070583
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00