Glandular Cells of Forest Musk Deer Autonomously Synthesize Sex Steroid Hormones

expression showing an upward trend. Elevated cholesterol increased several sex steroid hormone levels: pregnenolone, progesterone, 17α-hydroxypregnenolone, androstenedione, androsterone, and etiocholanolone by 4.12-, 1.46-, 33.42-, 2.06-, 3.11-, and 5.65-fold, respectively. These results collectively indicate that the musk glandular cells can synthesize sex steroid hormones de novo and suggest that cholesterol may regulate their biosynthesis in these cells.

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Publication Details

Journal
Biology
Published
2026-04-06
DOI
https://doi.org/10.3390/biology15070583
Primary Topic
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Type
article
Field-Weighted Citation Impact
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article

Glandular Cells of Forest Musk Deer Autonomously Synthesize Sex Steroid Hormones

Yele Zhang, Shuqiang Liu, Congxue Yao, Henghao Zhang et al.
Biology
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
article

Glandular Cells of Forest Musk Deer Autonomously Synthesize Sex Steroid Hormones

Yele Zhang, Shuqiang Liu, Congxue Yao, Henghao Zhang, Jingyao Hu, Habib Bati, Zexiu Zhang, Rongzeng Tan, Zhiyi Lou, Xiangyu Han, Xian An, Xin Dou, Yuetong Zhao
article en

Abstract

expression showing an upward trend. Elevated cholesterol increased several sex steroid hormone levels: pregnenolone, progesterone, 17α-hydroxypregnenolone, androstenedione, androsterone, and etiocholanolone by 4.12-, 1.46-, 33.42-, 2.06-, 3.11-, and 5.65-fold, respectively. These results collectively indicate that the musk glandular cells can synthesize sex steroid hormones de novo and suggest that cholesterol may regulate their biosynthesis in these cells.

BiologyVol. 15(7)
Beijing Forestry University (CN), Sino Biological (China) (CN)
Openalex Percentile: Top 29%
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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