Neonatal Submandibular Sialadenitis Without Abscess Formation: A Rare Cause of Neck Swelling

Acute neonatal sialadenitis is a rare condition, most commonly involving the parotid gland, whereas isolated submandibular gland involvement is uncommon and may pose diagnostic challenges. We report the case of a two-week-old term male infant who presented with right submandibular swelling in the absence of fever, systemic signs of infection, or abscess formation. Laboratory evaluation revealed leukocytosis with elevated inflammatory markers, and ultrasound imaging confirmed acute submandibular sialadenitis. The infant responded well to intravenous antibiotics without the need for surgical intervention. This case highlights the clinical variability of neonatal sialadenitis and emphasizes the importance of early recognition, appropriate imaging, and targeted antimicrobial therapy to prevent complications.

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Publication Details

Journal
Cureus
Published
2026-04-06
DOI
https://doi.org/10.7759/cureus.106526
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Neonatal Submandibular Sialadenitis Without Abscess Formation: A Rare Cause of Neck Swelling

Alaa W Qanbar, Rania Eladl, Sana Ahmed, Jarisha Ali et al.
Cureus
Salivary Gland Tumors Diagnosis and Treatment
article

Neonatal Submandibular Sialadenitis Without Abscess Formation: A Rare Cause of Neck Swelling

Alaa W Qanbar, Rania Eladl, Sana Ahmed, Jarisha Ali, Sania Shahid, Aqsa Shahid
article en

Abstract

Acute neonatal sialadenitis is a rare condition, most commonly involving the parotid gland, whereas isolated submandibular gland involvement is uncommon and may pose diagnostic challenges. We report the case of a two-week-old term male infant who presented with right submandibular swelling in the absence of fever, systemic signs of infection, or abscess formation. Laboratory evaluation revealed leukocytosis with elevated inflammatory markers, and ultrasound imaging confirmed acute submandibular sialadenitis. The infant responded well to intravenous antibiotics without the need for surgical intervention. This case highlights the clinical variability of neonatal sialadenitis and emphasizes the importance of early recognition, appropriate imaging, and targeted antimicrobial therapy to prevent complications.

CureusVol. 18(4)
University Geomedi (GE), Children's Specialty Group (US), Dubai Medical College (AE)
Good health and well-being
Openalex Percentile: Top 37%
Salivary Gland Tumors Diagnosis and Treatment
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