Biomarkers of oxidative damage as a tool to investigate frailty syndrome in older women

. For the subgroup, an increase in the Kyn/Trp ratio was observed in subjects with an altered Romberg test, concomitant with decreased levels of Trp, Met, Phe, and MDA (p-values = 0.0255, 0.0427, 0.0459, and 0.0173, respectively) when data were grouped according to the modified FTS-5. These results highlight the relevance of oxidative biomarkers as a tool for an early diagnosis of FS and its related complications.

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Publication Details

Journal
npj Aging
Published
2026-04-06
DOI
https://doi.org/10.1038/s41514-026-00372-y
Primary Topic
Frailty in Older Adults
Type
article
Field-Weighted Citation Impact
0.00
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article

Biomarkers of oxidative damage as a tool to investigate frailty syndrome in older women

Felipe Ávila, CAMILO LÓPEZ-ALARCÓN, Eduardo Fuentes Q, Iván Palomo et al.
npj Aging
Frailty in Older Adults
article

Biomarkers of oxidative damage as a tool to investigate frailty syndrome in older women

Felipe Ávila, CAMILO LÓPEZ-ALARCÓN, Eduardo Fuentes Q, Iván Palomo, Felipe Lagos, Ximena Pardo, M. Idalia Sepúlveda
article en

Abstract

. For the subgroup, an increase in the Kyn/Trp ratio was observed in subjects with an altered Romberg test, concomitant with decreased levels of Trp, Met, Phe, and MDA (p-values = 0.0255, 0.0427, 0.0459, and 0.0173, respectively) when data were grouped according to the modified FTS-5. These results highlight the relevance of oxidative biomarkers as a tool for an early diagnosis of FS and its related complications.

npj Aging
University of Talca (CL), Pontificia Universidad Católica de Chile (CL)
Openalex Percentile: Top 26%
Frailty in Older Adults
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